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The American Society of Anesthesiologists is an educational, research and scientific association of physicians organized to raise and maintain the standards of the medical practice of anesthesiology and improve the care of the patient.


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July 1, 2013 Volume 77, Number 7
John W. Severinghaus Lecture on Translational Science: ‘Understanding What Happens to Memory During Anesthesia’

Todd C. Sacktor, M.D. will present the Severinghaus Lecture at the ANESTHESIOLOGYTM 2013 annual meeting in San Francisco this October.

Dr. Sacktor, a Distinguished Professor of Physiology, Pharma-cology and Neurology at SUNY Downstate Medical Center, worked for 20 years on the molecular mechanisms of long-term memory storage. He discovered an isoform of protein kinase C, called PKMζ, which appears to have remarkable properties that allow it to store long-term memories. Inhibiting PKMζ erases old memories, and increasing the kinase enhances them. Next door was the laboratory of Ira Kass, Professor of Anesthesiology and Physiology and Pharmacology, and Jim Cottrell, Distinguished Professor and Chairman of the Department of Anesthesiology. While discussing science in the hallway, the three decided to look at the role of PKMζ in anesthesia. Together, they found that PKMζ plays a critical role in anesthesia-induced preconditioning. Further work on PKMζ shows how it may maintain memories of pain. Ongoing studies of PKMζ in transgenic animals reveal its crucial role in memory and suggest how anesthesia itself, through abnormal regulation of PKMζ, may cause cognitive abnormalities.

For a list of featured speakers at the ANESTHESIOLOGY™ 2013 annual meeting, visit

And click on either the EVENTS or FEATURED SPEAKERS buttons at the bottom of the banner on the annual meeting homepage.

See you in San Francisco!

2013 ASA Nicholas Greene, M.D. Award for Outstanding Humanitarian Contribution
Consistent with the catastrophic anesthesia crisis in low-income countries and the need for anesthesiologists to respond to disasters, provide care in humanitarian settings and educate/train those who would otherwise have no access to such expertise, the ASA membership has been reaching out to the world in these capacities for decades.

The ASA and the Committee on Global Humanitarian Outreach recognize the humanitarian contributions of an ASA member annually for Outstanding Volunteer Service and Humanitarian Contribution. A nomination application is available on the ASA GHO website at All applications are due Tuesday, July 31, 2013 to be reviewed at the GHO Committee meeting. The award will be presented at the ANESTHESIOLOGYTM 2013 annual meeting in October in San Francisco.

Anesthesia History Association Seeks Nominations for David M. Little Prizes
ach year the Anesthesia History Association awards David M. Little Prizes for the best original works on anesthesia history published the previous year in English in each of three categories: book, journal article and audio-visual medium. The prize is named after Dr. David M. Little, Jr. (1920-1981), longtime Chair of Anesthesia at Hartford Hospital in Connecticut. For many years, Dr. Little wrote the “Classical File” series of history columns for the Survey of Anesthesiology. Awards are announced each October at the Annual Dinner Meeting of the Anesthesia History Association during the ASA annual meeting. The 2013 awards are for works published in 2012. The deadline for this year’s award is September 2, 2013 and should be sent electronically to: George S. Bause, M.D. at

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