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ASA NEWSLETTER
 
 
September 2001
Volume 65
Number 9
   
Ralph Milton Waters: His Influence on the World and Me

Carlos P. Parsloe, M.D.


The purpose of this essay is to present two of my most poignant memories of “the Chief” and to describe the impact of his professionalism and leadership on the practice of anesthesiology throughout the world.

Two revealing personal episodes:

On a cold and wet Saturday afternoon in April 1946, I arrived in Madison, Wisconsin, for an interview with Ralph Waters, M.D. I was a candidate for a residency in anesthesiology. Correspondence from Chicago, where I was an intern, informed Dr. Waters that my schedule permitted only two opportunities to visit Madison. His short answer was “Come when you can.” I had no letters of recommendation and had no idea what to expect. The naivete of youth generally diminishes eventual difficulties. Once in Madison, I called him at home. The reply was, “Can you come to the hospital tomorrow at 1 p.m.?” “Yes,” I said, but I thought to myself, “Tomorrow is Sunday. How can a professor leave his home to interview a young unknown candidate from far away Brazil?”

I found him at his small office smoking a pipe, a relaxed, self-confident person. After five minutes of conversation, I decided that if accepted, I would go to Madison. That was the impact of his personality on a young man with little knowledge of anesthesia. I had given a number of general anesthetics in Rio de Janeiro with the Ombrédanne inhaler but without any real knowledge of what I was doing. Thankfully, human beings are resilient to nonphysiological assaults. That the world’s first and foremost professor of anesthesia (something that I did not realize at the time!) left his home on a Sunday to interview a candidate from a remote country, with no special gifts of any kind, is testimony to the generosity of his personality.

I was accepted, but I never asked Dr. Waters the basis for his decision. That one-hour interview literally changed my whole life. Fifty-five years have elapsed and never for one moment have I had reason to regret my decision. I went to Madison with no particular direction in life and left with a rosy future, a finite background of knowledge, a crowd of life-long friends, a good Wisconsin wife and the most pleasant memories of two unforgettable years, working and learning in a most hospitable atmosphere.

The second episode occurred on a fateful morning during my second year. I started to anesthetize a very young girl with bronchiectasis for lobectomy. She was frightened, repeating, “I am going to die.” I did not believe her until her heart stopped. Resuscitation with an open thorax proved useless, and after an hour, we gave up. I was extremely upset and did not know what to expect.

Later in the day, I met with the Chief. I had made meticulous notes of the whole unfortunate accident. I was greeted with, “Carlos, tell me what happened.” After listening without interruption, he told me, “Well, those things unfortunately can happen, you should not blame yourself. We will discuss this death at the Wednesday conference.”

I was one of the last to arrive at the room. To my surprise, the professor of thoracic surgery, who was the patient’s surgeon, was sitting at Dr. Waters’ side. Dr. Waters began, “There was an unfortunate death on induction. Would the surgeon describe the patient’s condition?” The patient was a chronic bronchiectatic with profuse secretions that could not be controlled. She needed removal of the affected lung to improve her condition. I then explained how I started giving cyclopropane to a very frightened girl while she was crying. The heart had stopped before induction was complete. Profuse secretions prevented proper ventilation, and all efforts at resuscitation had failed. Dr. Waters then thanked the surgeon and excused him. While I had expected the worst, Dr. Waters aimed no recriminations or blame at me. In retrospect, hypoxia and catecholamine surge combined with cyclopropane stopped the heart. The lesson was learned. What could have been a remorseful episode turned out to be a learning one, benefiting everyone and relieving my guilty feeling.

These two episodes tell a great deal about how Dr. Waters conducted his training. In an emotionally charged situation, he persuaded the surgeon to come to the meeting and to alleviate my utter discomfort. I felt protected and could continue my training without feeling despair. Those two episodes, which remain vividly clear in my memory after 55 years, have generated a profound humility and gratitude for the wisdom and leadership of Dr. Ralph Waters.

I vividly remember seeing the Chief daily in the operating rooms administering anesthesia. I do not remember hearing him tell me or anyone else what to do. Residents needed only to imitate his demeanor and activities. We watched him gently apply a mask and proceed with a smooth cyclopropane induction. Then we tried as hard as we could to emulate him, realizing all the time that this was no small task. Of course, those were the days of a mask, a to-and-fro canister and a five-liter rebreathing bag. Cyclopropane and sometimes nitrous oxide with oxygen were the “joy” of our practice. The “joy” included adapting the mask to the patient’s face, often over a nasogastric tube and using controlled manual ventilation assisted by an oropharyngeal airway.

He gave a few lectures to the student classes. The residents’ didactic teaching consisted of the Monday evening literature review and the Wednesday afternoon case discussions. In addition to Dr. Waters, Sidney Orth, M.D., from pharmacology always had answers to many questions about drug effects, and Noel A. Gillespie, M.D., originally from England, had dissenting views on just about every clinical situation. The frank and lively exchange of opinions provided for a rich learning ambiance.

Dr. Waters’ International Projection
The international stature of Dr. Waters at the time was most remarkable. Madison was the mecca of anesthesia during the 1930s and 1940s. Travel was difficult, and correspondence by mail was the best available means of communication. The Waters archive at the Department of Anesthesiology, University of Wisconsin, is full of revealing letters. Most notable, perhaps, is the correspondence with Arthur E. Guedel, M.D., and Geoffrey Kaye, M.D., from Australia. It conveys insight into important problems of the time, such as arrhythmias with cyclopropane.

The Anesthetists Travel Club was formed early and provided an opportunity to gather the few anesthesiologists in the United States and Canada to meet and exchange opinions. Large congresses did not exist. As a consequence, Waters did not travel much. Instead, colleagues from many countries came to Madison to imbibe the Chief’s simple and basic teachings. These are expressed in the book that he edited, Fundamentals of Anesthesia, published by the American Medical Association. The book, which was my first source of information, emphasizes airway and ventilation as fundamental to patient safety.


Ralph M. Waters, M.D., right, with Torsten Gordh, M.D., from Sweden at the Third World Congress of Anaesthesiology, September 20-26, 1964, in São Paulo, Brazil.

Sir Robert R. Macintosh, D.M., visited with Dr. Waters prior to becoming the first professor of anesthesia in the United Kingdom and starting a new department at Oxford. He came to exchange ideas with Dr. Waters and to absorb the concept of a triad of clinical practice, teaching and research as the basic tenet of a university department. M. Digby Leigh, M.D., from Canada was a resident with Dr. Waters before establishing the subspecialty of pediatric anesthesia and becoming a professor in Montreal. The first four Swedish anesthesiologists were trained by Dr. Waters, who received the Vasa Medal from the Swedish government for this achievement in 1948. Eric Nilsson, M.D., from Lund and Karl-Gustav Dhuner, M.D., from Gothenburg were fellow residents with me. Torsten Gordh, M.D., and Olle Friberg, M.D., finished before I started.

We residents learned about the Vasa Medal by reading the local newspaper the day following the presentation by the Swedish Consul in Chicago. This reveals the modesty of Dr. Waters. Jone Wu, M.D., a pharmacologist from Shanghai, became a resident during my time and returned to China to establish a department in Shanghai. He is the father and grandfather of all Chinese anesthesiologists. He, like Dr. Gordh in Sweden, was the first professor of anesthesiology in his country. Professor Juan Nesi from Buenos Aires was a notable visitor. Martinez Curbello, M.D., from Havana, Cuba, who had introduced continuous peridural anesthesia with a ureteral catheter in 1947, demonstrated the technique in Madison. Professor Edward Pask from the United Kingdom also visited. Olive Jones, M.D., from Oxford spent one year mostly engaged in neurosurgical anesthesia, her specialty. Colleagues from India, Brazil, Mexico, Peru and Uruguay learned the safe conduct of anesthesia with Dr. Waters in Madison. As a result, anesthesiology in Latin America became physician-based and well developed since 1940.

Waters did travel to England in 1936 at the invitation of the British Medical Association to lecture on cyclopropane and to receive honorary membership in the Royal Society of Medicine. That was the only time he left the United States during his professorship. After retirement in 1950, he traveled to Copenhagen to become a teacher in the World Health Organization training center for anesthesiologists. He then moved to Orlando, Florida, and refused all invitations to travel. Nevertheless, in preparation for the Third World Congress of Anaesthesiology in São Paulo, Brazil, in 1964, I was determined to have Dr. Waters give the opening lecture. Repeated invitations were nicely declined. Desperate to achieve my desire, I discussed the problem with Perry P. Volpitto, M.D. He advised me to invite Mrs. Waters. The Chief came to São Paulo and gave a short but incisive opening speech, which was later published in Survey of Anesthesiology. It illustrates his knowledge of the history of anesthesia as well as his concern for the training of physicians as anesthesiologists throughout the world.

The golden days of the new specialty of anesthesiology produced many memories for those who were privileged to have met and worked with the Ralph Waters in Madison. The genealogical tree of Waters alumni prepared by Lucien E. Morris, M.D., (see pages 22-23) depicts the solid trunk and branches into most states in the United States and four continents of the world. This was the extent of the influence of this great pioneer in anesthesiology.



  Carlos P. Parsloe, M.D., is an anesthesiologist practicing at Hospital Samaritano, São Paulo, Brazil.


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