emember the movie "The Perfect Storm"?
It was essentially a true story and a real meteorological
oddity — there was Hurricane Grace in the
Atlantic, energy coming across from the Great Lakes
and a frontal system in the New England area. Over
time the energy from these three storms combined
out in the Atlantic to form one perfect storm.
In similar fashion, four factors have converged
to produce a real conundrum for anesthesiology regarding
intraoperative awareness and the role of brain function
(consciousness) monitoring:
1. There are at least two patients whose episodes
of painful intraoperative awareness affected them
to the degree that they are now passionate advocates
of eliminating this problem. Their experiences
have received widespread attention by the news
media.
2. In the last few years, several large clinical
studies on intraoperative awareness have appeared,
and the number of ASA abstracts and editorial
discussions dealing with this issue has significantly
increased.
3. There are companies that have developed electroencephalography-based
monitors that promise to assist in preventing
awareness. One monitor is already being marketed
for this purpose, and all of them will likely
generate profits for the manufacturers.
4. There are a number of anesthesiologists who
have not embraced the technology and loudly question
either the value of the monitors or the way they
are marketed.
This problem gained a sense of urgency when the
Joint Commission on Accreditation of Healthcare
Organizations jumped into the fray in October with
its Sentinel Event Alert.
Many on all sides wonder, “Why doesn’t
ASA do something — like write a standard?”
One point needs to be stressed. Anesthesiologists
are professionals. They do not require ASA or any
other entity telling them how to practice. Anesthesiologists
evaluate new knowledge (hopefully much of it presented
to them by ASA or its journal) and decide whether
or not to incorporate new developments into their
practices. As an example, ASA has not told anesthesiologists
to use perioperative beta blockade to minimize ischemia,
but many anesthesiologists have already adopted
it into their practices. Every day each of us individually
does what we believe is best for our patients without
the need for mandated standards.
Thus, not suprisingly, this unusual confluence of
factors about awareness has, to date, produced much
more heat than light. ASA decided that one way to
help patients and anesthesiologists alike was to
develop a practice parameter and appointed a task
force to do just that. ASA has a well-established
process in developing practice parameters; the first,
on the difficult airway, was published in 1993,
and 12 more have been published since. In addition
to this practice parameter, four others are currently
being written.
When the task force was appointed, some were unhappy
with ASA’s decision to exclude those who had
a conflict of interest on this subject. The argument
was made that those with conflicts also were those
with the most knowledge of the technology. ASA,
however, used what it believes to be a routine policy
among standard-setting bodies by excluding those
with a conflict. There will be a special effort
made to include the views of the excluded experts.
Part of the usual practice parameter process is
to present a draft parameter to an open forum at
one or more major anesthesiology meetings in order
to allow feedback from the membership. Because of
the controversy surrounding awareness monitoring,
the task force decided to conduct an additional
open forum at the beginning of the process to get
a better sense of the environment. It was held at
the ASA Annual Meeting, and each of the six companies
producing monitors was invited to present.
Meanwhile, in response to member requests, the Committee
on Quality Management and Departmental Administration
has made available a sample department policy on
intraoperative awareness. This document may be found
on the “Members Only” section of the
ASA Web site.
It was a real eye opener for me, not so much on
the issue of awareness but rather for my personal
realization of the lack of attention to brain monitoring.
I heard a number of profound statements that morning,
and I am sorry that I cannot attribute this wisdom
to the proper authors.
It was pointed out that we readily accept a particular
heart rate as optimum for a given patient but give
little attention to a precise level of anesthetic
depth. My personal and naive view of anesthetic
depth has been that as long as the patient was not
aware and/or in pain and was not dead, then everything
was OK. The only time I usually pay scrupulous attention
to anesthetic depth is when I am very concerned
with hemodynamic parameters such as myocardial oxygen
demand or contractility. We readily accept the premise
that there is an optimum heart rate for an anesthetized
patient and that additional comorbid conditions
may narrow the acceptable heart rate range. Why
is it so hard to accept that there will be an optimum
depth of anesthesia?
Another thought-provoking question: if you were
to personally suffer a nonlife-threatening perioperative
complication, which would you rather have, a small
stroke or a small myocardial infarction?
Our current level of sophistication of brain monitoring
is analogous to the three lead “bullet”
electrocardiography monitor I used 30 years ago.
Compare that to S-T segment analysis, transesophageal
echocardiography, thermodilution cardiac outputs
and pulmonary artery pressures available today.
Do we use these sophisticated cardiac monitors because
we need to or because we can? When the only tool
you have is a hammer, then the whole world is a
nail. If we could monitor the brain with the same
level of sophistication as the heart, would we?
You bet!
Another part of the puzzle is the effect of anesthetic
depth on long-term outcome. The Anesthesia Patient
Safety Foundation (APSF) recently organized an expert
panel on “The Long-Term Impact of Surgery
and Anesthesia” that strongly suggested that
the perioperative experience may have a much longer
effect than previously appreciated and that depth
of anesthesia may be one of the factors affecting
outcome. The early data raises more questions than
answers, but this is a profound question that demands
an answer.
My opinion is that part of the future of anesthesiology
is in more sophisticated monitoring of both the
function of the brain as well as anesthetic effect.
We may find that developments in monitoring the
brain will take the science of anesthesiology to
a different level. We have to do what is best for
our patients based on science and not paint ourselves
into a corner by opposing brain function monitoring
because of external forces. Maybe we should stop
worrying about how companies market their devices.
Our focus ought to be on encouraging research on
neurological monitoring, optimum anesthetic depth
and long-term outcomes by anesthesiologist scientists
and technology companies.
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Orin F. Guidry, M.D., is Chair, Department of
Anesthesiology, Ochsner Clinic and Ochsner Foundation
Hospital, New Orleans, Louisiana. |
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